Table 4.

Results from multivariable logistic regression analysis at baseline.

	Quiescent vs most severe, OR [95% CI]	p-value	Quiescent vs all other patients, OR [95% CI]	p-value	Most severe vs all other patients, OR [95% CI]	p-value
Age at diagnosis, years	1.03 [1.01–1.06]	0.010*	1.02 [1–1.04]	0.093	0.97 [0.95–0.99]	0.003*
Montreal location
L1	REF		REF		REF
L2	0.79 [0.39–1.60]	0.508	0.71 [0.39–1.30]	0.268	1.04 [0.60–1.81]	0.900
L3	0.44 [0.19–1.00]	0.050*	0.44 [0.21–0.92]	0.029*	1.54 [0.86–2.74]	0.144
Montreal behaviour
B1	REF		REF		REF
B2	0.70 [0.31–1.56]	0.383	0.78 [0.39–1.57]	0.487	1.16 [0.64–2.11]	0.629
B3	0.96 [0.26–3.46]	0.944	0.44 [0.17–1.16]	0.096	0.39 [0.15–1.02]	0.054
Perianal disease	0.91 [0.35–2.36]	0.912	0.77 [0.34–1.74]	0.533	0.72 [0.35–1.46]	0.357
Upper GI involvement	0.44 [0.12–1.64]	0.221	0.33 [0.11–1.02]	0.540	0.77 [0.34–1.72]	0.517
Gender, male	1.04 [0.56–1.91]	0.910	0.88 [0.52–1.48]	0.625	0.97 [0.61–1.56]	0.906
Smoking at diagnosis	0.43 [0.24–0.76]	0.004*	0.44 [0.27–0.73]	0.001*	1.63 [1.05–2.55]	0.031*
Surgery at diagnosis	2.99 [1.07–8.34]	0.036*	2.93 [1.34–6.39]	0.007*	0.52 [0.21–1.30]	0.160

Phenotype according to Montreal classification, disease location was defined as ileal involvement [L1], exclusive colonic involvement [L2] or ileocolonic involvement [L3]. Disease behaviour was defined as non-stricturing/non-penetrating [B1], stricturing [B2], or penetrating [B3].

GI, gastrointestinal; OR, odds ratio; 95% CI, 95% confidence interval; REF, reference category.

*p-value below 0.05