Table 1.

Summary of the criteria applied for HFpEF phenotypic selection.

Metrics	HFpEF Phenotypic Criteria
CaTA at 0.5 Hz pacing without ISO	No smaller than 70% of the model baseline cell CaTA under the same condition.
CaTA increase in response to increased pacing rate at the absense of ISO	For each rate increment (0.5 to 1.0 Hz and 1.0 to 2.0 Hz), the increase of CaTA is smaller than that of the model baseline cell.
CaTA increase in response to 1.0 μM ISO	At all pacing rates, the increase of CaTA is smaller than that of the model baseline cell.
CaT decay time	Longer than that of the model baseline cell, at each pacing rate, with and without ISO.