Table 3.
Reduced model: two-part model effects between fasting insulin and CRP among adults without diabetes
| Covariate | Logit model | GLM model | Combine two-part model Predictive margins |
||
|---|---|---|---|---|---|
| OR | p-value | β | p-value | Predicted CRP mg/L (CI) | |
| Age, years | 1.05 | <.001 | 0.02 | .013 | |
| 20–39 | 3.56 (3.26, 3.85) | ||||
| 40–59 | 4.07 (3.72, 4.42) | ||||
| 60–85 | 4.62 (4.03, 5.22) | ||||
| Sex | |||||
| Male | Reference | 3.78 (3.31, 4.25) | |||
| Female | 0.83 | .373 | 0.73 | .001 | 4.22 (3.90, 4.53) |
| Race | |||||
| Non-Hispanic White | Reference | 3.92 (3.57, 4.27) | |||
| Mexican/other Hispanic | 2.29 | .013 | 0.06 | .851 | 4.41 (3.80, 5.03) |
| Non-Hispanic Black | 0.75 | .204 | 0.41 | .149 | 4.72 (4.23, 5.21) |
| Other race/multi | 0.51 | .037 | − 0.81 | <.001 | 2.96 (2.51, 3.41) |
| Poverty-income ratio | 1.02 | .673 | − 0.08 | .168 | |
| < 130% FPR | 4.78 (4.35, 5.22) | ||||
| 130–349% FPR | 4.18 (3.83, 4.53) | ||||
| >=350% FPR | 3.51 (3.17, 3.86) | ||||
| Smoking | |||||
| Non/former smoker | Reference | 3.83 (3.46, 4.21) | |||
| Current smoker | 1.26 | .280 | 1.26 | <.001 | 4.62 (4.08, 5.17) |
| Physical activity | |||||
| No | Reference | 5.19 (4.66, 5.72) | |||
| Yes | 1.08 | .757 | − 0.86 | .008 | 3.55 (3.21, 3.89) |
| Fasting Insulin, pmol/L | 1.02 | <.001 | 0.03 | <.001 | |
| < 60 | 2.86 (2.66, 3.06) | ||||
| 60–119 | 4.39 (3.98, 4.80) | ||||
| ≥ 120 | 7.58 (6.37, 8.79) | ||||
Mexican/other Hispanic: Mexican or other Hispanic ethnicity; Other race/multi: other race or Multiracial; CRP: C-reactive protein; OR: odds ratio; CI: confidence interval; FPR: federal poverty ratio
Reduced Model: controlling for age, sex, race, socioeconomic status (poverty-income ratio), smoking status, physical activity, and fasting insulin
Two-part regression model used; reference group is the reference group used for each categorical variable
Each level of categorical variable used to provide a predicted CRP based on the model
National estimates based on complex survey design