Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 10;16:16. doi: 10.1186/s13024-021-00437-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 7 — Deletion of Ddit3 prevents abnormal retinal function induced by the AAV8-mediated high dose of HMOX1. a, b Western blots of neural retinas from Ddit3+/+ (n = 3) and Ddit3−/−mice (n = 3) 2 weeks after infection with a high dose of AAV8-GPF or AAV8-HMOX1, using anti-HMOX1, anti-GFP or anti-DDIT3 antibodies (a) and corresponding quantitative bar graphs (b) (Error bars: SD; one-way ANOVA; *, p < 0.05; **, p < 0.01; ***p < 0.001). c ERG traces of 2-month-old Ddit3+/+ (left panels) and Ddit3−/− (right panels) mice 2 weeks after infection with the high dose of AAV8-GFP or AAV8-HMOX1. d, e Quantification of ERG amplitudes in rod response (d) and standard response (e) according to the ERG trace results from c (Error bars: SD; n = 4, one-way ANOVA; *, p < 0.05; **, p < 0.01)