Table 1.
Test set (available data) (n = 12) | Training set only (n = 136) | Total (n = 148) | |
---|---|---|---|
Age (years) | |||
Median | 44 | 46 | 46 |
Min-max | 30-82 | 27-82 | 27-82 |
Q1 (first quartile) - Q3 (third quartile) | 41.5-60.5 | 38-56 | 38-56 |
20-29 | 0 (0.0%) | 5 (3.7%) | 5 (3.4%) |
30-39 | 2 (16.7%) | 39 (28.7%) | 41 (27.7%) |
40-49 | 6 (50.0%) | 42 (30.9%) | 48 (32.4%) |
50-59 | 1 (8.3%) | 25 (18.4%) | 26 (17.6%) |
60-69 | 1 (8.3%) | 17 (12.5%) | 18 (12.2%) |
70-79 | 1 (8.3%) | 7 (5.1%) | 8 (5.4%) |
80-89 | 1 (8.3%) | 1 (0.7%) | 2 (1.4%) |
Ethnicity | |||
Hispanic | 2 (16.7%) | 27 (19.9%) | 29 (19.6%) |
Non-Hispanic | 10 (83.3%) | 106 (77.9%) | 116 (78.4%) |
Unknown/not reported | 0 (0.0%) | 3 (2.2%) | 3 (2.0%) |
Race | |||
Unknown/not reported | 0 (0.0%) | 4 (2.9%) | 4 (2.7%) |
Asian | 1 (8.3%) | 2 (1.5%) | 3 (2.0%) |
Black/African American | 2 (16.7%) | 15 (11.0%) | 17 (11.5%) |
American Indian/Alaskan | 0 (0.0%) | 2 (1.5%) | 2 (1.4%) |
More than 1 race | 0 (0.0%) | 1 (0.7%) | 1 (0.7%) |
White | 9 (75.0%) | 112 (82.4%) | 121 (81.8%) |
Performance status | |||
0 | 9 (75.0%) | 110 (80.9%) | 119 (80.4%) |
1 | 3 (25.0%) | 26 (19.1%) | 29 (19.6%) |
Histology | |||
Adenocarcinoma, unsp. | 0 (0.0%) | 29 (21.3%) | 29 (19.6%) |
Adenosquamous | 0 (0.0%) | 4 (2.9%) | 4 (2.7%) |
Squamous cell carcinoma | 12 (100.0%) | 103 (75.7%) | 115 (77.7%) |
FIGO stage | |||
I | 1 (8.3%) | 28 (20.6%) | 29 (19.6%) |
II | 7 (58.3%) | 77 (56.6%) | 84 (56.8%) |
III | 3 (25.0%) | 23 (16.9%) | 26 (17.6%) |
IV | 1 (8.3%) | 8 (5.9%) | 9 (6.1%) |
Site of disease | |||
Cervix | 11 (91.7%) | 128 (94.1%) | 139 (93.9%) |
Vagina | 1 (8.3%) | 8 (5.9%) | 9 (6.1%) |
Planned brachytherapy | |||
HDR | 12 (100.0%) | 132 (97.1%) | 144 (97.3%) |
LDR | 0 (0.0%) | 4 (2.9%) | 4 (2.7%) |
Planned IG-IMRT | |||
No | 0 (0.0%) | 33 (24.3%) | 33 (22.3%) |
Yes | 12 (100.0%) | 103 (75.7%) | 115 (77.7%) |
Randomized treatment | |||
RT + CIS | 4 (33.3%) | 70 (51.5%) | 74 (50.0%) |
RT + CIS + 3AP | 8 (66.7%) | 66 (48.5%) | 74 (50.0%) |
Abbreviations: 3AP = Triapine; CIS = cisplatin; FIGO = International Federation of Gynecology and Obstetrics; HDR = high-dose-rate; IG-IMRT = image guided intensity modulated radiation therapy; LDR = low dose rate; RT = radiation therapy.