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. 2021 Mar 9;7(1):e001508. doi: 10.1136/rmdopen-2020-001508

Table 1.

Patient characteristics

N % Median (IQR)
Patients 333
Death 114
Age, years 71 (62–77)
 <65 104 31.2
 65–74 109 32.7
 ≥75 120 36.0
Female 210 63.1
RA and PMR 52 15.6
Psoriatic arthritis and spondylarthritis 0 0.0
Primary vasculitis syndrome 116 34.8
Systemic lupus erythematosus 49 14.7
Inflammatory myositis 60 18.0
Systemic sclerosis 13 3.9
Others 43 12.9
Concomitant ILD 122 36.6
Admission to an advanced treatment hospital 94 28.2
Bronchoscopy 36 10.8
Intensive care management 37 11.1
Ventilator use 83 24.9
Length of hospital stay after starting PCP treatment, days 33 (4–37)
Glucocorticoid therapy
Concomitant glucocorticoid use 322 96.7
Glucocorticoid pulse therapy 103 30.9
Antibiotics for PCP
ST monotherapy 214 64.3
Others 119 35.7
PTM group 80 24.0
 PTM monotherapy 32 8.4
 ST → PTM 48 14.4
ATO group 29 8.7
 ATO monotherapy 9 2.7
 ST → ATO 20 6.0
 Other combinations 10 3.0
Adjunctive therapy
Gamma-globulin 31 9.3
Albumin 40 12.0
Empiric antibiotic therapy 245 73.6
Antifungal drugs 110 33.0
Anticytomegalovirus drugs 56 16.8

ATO, atovaquone; ILD, interstitial lung disease; PCP, pneumocystis pneumonia; PMR, polymyalgia rheumatica; PTM, pentamidine; RA, rheumatoid arthritis; ST, sulfamethoxazole/trimethoprim.