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. 2021 Mar 9;9(3):e002068. doi: 10.1136/jitc-2020-002068

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Best response by patient based on change in tumor size. All treated patients with best overall response (n=33). Blue number=percentage of tumor cells at baseline with positive PD-L1 membrane staining. Dashed lines at –30% and 20% represent the thresholds for SD; neither an increase in size of more than 20% nor a decrease in size of more than 30% since the initial baseline measurement. BID, two times per day; PD, progressive disease; PD-L1, programmed death-ligand 1; PR, partial response; QD, one time per day; SD, stable disease.