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. 2021 Feb 24;10:618215. doi: 10.3389/fonc.2020.618215

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Copyright © 2021 Wang, Yan, Guan, Dong, Zhao, Wu, Tian and Hao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationships between pancreatic ductal adenocarcinoma (PDAC) and normal pancreatic tissues. (A) Significant enrichment of immune-related pathways in tissues from patients with PDAC, compared with normal pancreatic tissues. NES, normalized enrichment score. (B) Volcano plot of 871 metabolism-related genes differentially expressed in PDAC and normal pancreatic samples. (C) Heatmap showing the expression of IRGs in each sample. (D) Functional analysis of 838 metabolism-related genes.