Table 1.
Drug | Dose (mg/ml) | Ear swelling (μm, mean ± SD, n = 7) |
Scratching bouts (60 min, mean ± SD, n = 7) |
---|---|---|---|
Vehicle | 0 | 363 ± 46 | 108 ± 28 |
BMX-001 | 0.04 | 374 ± 48 | ND |
0.1 | 388 ± 28 | ND | |
0.4 | 385 ± 56 | 136 ± 29 | |
BMX-010 | 0.04 | 327 ± 59 | ND |
0.1 | 356 ± 29 | ND | |
0.4 | 327 ± 43 | 130 ± 62 | |
Triamcinolone | 0.1 | 58 ± 35** | ND |
Results are expressed as mean ± 1 SD (n = 7 per group)
P < 0.01 (Dunnett’s multiple comparison test) vs. vehicle-only control group ND not determined