TABLE 4.
Effects of chlorpyrifos, Artemisia campestris essential oil (ACEO), vitamin C, and their combination (ACEO + CPF and VitC + CPF) on TBARS levels and the activities of enzymatic antioxidants in liver and kidney of control (C) and experimental rats.
| Treatment and parameters | Control | ACEO | CPF | ACEO + CPF | VitC | VitC + CPF | |
| TBARS (nmol MDA/mg protein) | Liver | 0.61 ± 0.06 | 0.61 ± 0.09 | 1.12 ± 0.1** | 0.58 ± 0.06# | 0.58 ± 0.09 | 0.57 ± 0.09# |
| Kidney | 2.88 ± 0.11 | 3.44 ± 0.66 | 5.04 ± 1.14** | 3.55 ± 0.17## | 3.39 ± 0.31 | 3.67 ± 0.42## | |
| SOD (Units/mg protein | Liver | 19.73 ± 1.21 | 14.31 ± 3.95 | 11.8 ± 1.14** | 17.56 ± 2.29## | 13.99 ± 1.75 | 15.44 ± 1.42## |
| Kidney | 21.48 ± 4.28 | 23.95 ± 3.3 | 18.03 ± 3.31* | 20.32 ± 3.2# | 25.98 ± 3.15 | 16.43 ± 2.48# | |
| CAT (μmol H2O2/min/mg protein) | Liver | 198.8 ± 10.03 | 177.59 ± 6.33 | 142.97 ± 7.34** | 185.37 ± 8.8## | 183.6 ± 4.7 | 197.61 ± 5.22## |
| Kidney | 100.62 ± 11.04 | 86.31 ± 8.6 | 74.87 ± 6.34** | 97.23 ± 6.61## | 98.25 ± 9.46 | 92.17 ± 7.56## | |
| GPx (μmol GSH/min/mg protein) | Liver | 2.32 ± 0.27 | 2.53 ± 0.23 | 1.4 ± 0.48* | 2.08 ± 0.48## | 2.48 ± 0.3 | 2.06 ± 0.13## |
| Kidney | 8.35 ± 0.72 | 7.75 ± 0.37 | 4.32 ± 0.4** | 6.61 ± 1.04## | 7.90 ± 1.31 | 6.79 ± 1.2 |
Values are mean ± SEM; n = 6 rats in each group. Statistical significant variations are compared as follows: CPF, ACEO, ACEO + CPF, VitC, and VitC + CPF treated groups compared to control group; * indicates significantly different when p < 0.05, ** indicates highly significantly different when p < 0.01, CPF group compared to (ACEO + CPF and VitC + CPF) group; # indicates significantly different when p < 0.05, ## indicates highly significantly different when p < 0.01.