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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Matter. 2021 Jan 6;4(1):26–53. doi: 10.1016/j.matt.2020.10.002

Figure 3. Drug Release Driven by the Cascade of Stimuli-Induced Heating and Heat-Induced Structural Changes of Drug Carriers.

Figure 3.

(A) GNR core-satellite superstructures prepared by different DNA linker sequences.

(B) Drug release from GNR superstructures triggered by laser irradiation for different time.

(C) Drug release from GNR superstructures triggered by different photothermal temperatures.

(A) to (C) reproduced with permission from Raeesi et al.32 Copyright 2016, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

(D) Schematic illustration of photothermal heating-triggered drug release from yolk-shell Fe3O4@Au NPs.

(E) Photothermal heating curves of the yolk-shell Fe3O4@Au NPs under laser irradiation.

(F) Drug release from the yolk-shell Fe3O4@Au NPs at different temperatures or under laser irradiation.

(D) to (F) reproduced with permission from Lin et al.34 Copyright 2017, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

(G) Schematic illustration of nanocarrier (AuNG-Lips) destruction caused by photothermal heating-triggered bubble generation.

(H) Photothermal heating curves of the AuNG-Lips under laser irradiation.

(I) Ultrasound images showing photothermal heating-triggered bubble generation from the AuNG-Lips.

(J) Drug release from the AuNG-Lips at 37°C or 42°C (maintained by laser irradiation). (G) to (J) reproduced with permission from Chuang et al.35 Copyright 2016, Elsevier.