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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Matter. 2021 Jan 6;4(1):26–53. doi: 10.1016/j.matt.2020.10.002

Figure 7. Drug Release Driven by the Cascade of Stimuli-Induced Hypoxia and Hypoxia-Induced Dissociation of Nanocarrier.

Figure 7.

(A) Schematic illustration showing the application of DOX/CP-NI NPs for drug delivery.

(B) In vitro drug release from DOX/CP-NI NPs in different conditions.

(C) Pulsatile release profile of DOX/CP-NI NPs at different pH for light/dark cycles.

(D) CLSM images of HeLa cells treated with different formulations.

Reproduced with permission from Qian et al.42 Copyright 2016, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.