Figure 7.

Differentially expressed genes between infected (unvaccinated) and infected (vaccinated) mice. (a) PCA plot of gene expression in mice. (b) Volcano plot of differential gene expression in infected (unvaccinated) versus infected (vaccinated) mice. Genes were considered significantly differentially expressed for a log 2 fold change and p value of 0.05. The top 10 (up – and/or downregulated) differentially expressed genes are shown. (c) Heatmap of immune-associated gene expression. (d) Gene ontology enrichment of differential genes in infected (unvaccinated) versus infected (vaccinated) mice