Table 1.

The degree of histopathological findings.

	IRD	BIR	SG	p*	pa	pb	pc
TN	0(0-0)	3(3-3)	0(0-0)	<0.001	0.001	1.000	0.001
ICF	1(0-1)	3(2-3)	0(0-0)	0.001	0.047	0.501	<0.001
AC	0(0-0)	3(3-3)	0(0-0)	<0.001	0.001	1.000	0.001
TD	0(0-1)	3(3-3)	0(0-0)	<0.001	0.004	1.000	0.001
PTFK	0(0-0)	3(3-3)	0(0-0)	<0.001	0.001	1.000	0.001

Results were presented as median(minimum-maximum).

AC: apoptotic bodies; ICF: intratubular cast formation; PTFK: proximal tubule brushy edge loss; TD: tubular dilatation; TN: tubular necrosis.

*Kruskal Wallis test was used. Dunn’s test was used for pairwise comparisons of ^aIRD-BIR, ^bIRD-SG, ^cBIR-SG.

0 – normal, 1 – mild damage, 2 – moderate damage and 3 – severe damage.