Table 3. Top 10 DMR results with complete probe set.
Chr | start | end | Nearest gene (distance to TSS) | N | b | se | p-value |
---|---|---|---|---|---|---|---|
8 | 87355594 | 87355773 | WWP1 (+717) | 3 | -0.40 | 0.10 | 1.05 x 10−04 |
22 | 41252959 | 41253041 | XPNPEP3 (-102) | 3 | -0.31 | 0.08 | 1.17 x 10−04 |
19 | 50380748 | 50380763 | TBC1D17 (+74) | 2 | -0.49 | 0.13 | 1.24 x 10−04 |
7 | 1610694 | 1610747 | PSMG3 (-1092) | 2 | -0.06 | 0.02 | 1.35 x 10−04 |
9 | 99540409 | 99540427 | ZNF510 (-80) | 3 | -0.44 | 0.11 | 1.39 x 10−04 |
4 | 59850015 | 59850171 | None | 2 | 0.18 | 0.05 | 1.42 x 10−04 |
6 | 32829062 | 32829208 | PSMB9 (+7197) | 3 | -0.14 | 0.04 | 1.47 x 10−04 |
3 | 49157911 | 49158377 | USP19 (+120) | 6 | -0.33 | 0.09 | 1.64 x 10−04 |
2 | 98262546 | 98262568 | COX5B (+54) | 2 | -1.05 | 0.28 | 1.72 x 10−04 |
3 | 45017855 | 45017955 | ZDHHC3 (-231) | 2 | -0.72 | 0.19 | 1.90 x 10−04 |
Chr = chromosome, N = number of probes within DMR, b = change in DAS28 upon 1% difference in baseline methylation.