Skip to main content
. 2021 Mar 10;16(3):e0246454. doi: 10.1371/journal.pone.0246454

Table 2. Subgroup analyses for studies on anxiety.

Subgroup analysis No. of studies Prevalence % (95% CI) I2 Between-group difference
Region East Asia 40 20.5 (15.7–25.8) 99.6%
Middle-East 7 28.9 (21.6–36.8) 96.4%
Europe 4 23.9 (19.6–28.4) 82.9%
South Asia 3 21.0 (11.7–31.4) -b
North America 2a 14.8 (13.9–15.7) -
p<0.001
Sampling method Non-random 52 23.8 (19.7–28.1) 99.4%
Random 5 7.9 (4.4–12.3) 94.0%
p<0.001
Screening tool GAD-7 29 20.8 (17.2–24.7) 98.7%
SAS 9 10.1 (5.6–15.6) 98.6%
DASS-21 6 27.0 (16.1–39.4) 98.8%
HADS 3 32.0 (10.8–58.1) -
GAD-2 3 22.1 (10.1–37.2) -
PHQ-4 2 24.1 (20.6–27.7) -
HAMA 2 26.8 (25.0–28.8) -
p<0.001
Contact with infected patients >50% 15 25.7 (17.4–34.9) 98.8%
≤50% 12 17.4 (14.5–20.4) 96.2%
p = 0.06c

Abbreviation: DASS = Depression Anxiety Stress Scales; GAD = Generalised Anxiety Disorder Assessment; HADS = Hospital Anxiety and Depression Scale; HAMA = Hamilton Anxiety Rating Scale; PHQ = Patient Health Questionnaire; SAS = Zung’s Self-Rating Anxiety Scale

aOnly subgroups with two or more included studies are presented

bI2 statistic provided for subgroups with four or more included studies

cBorderline significance