TABLE 2.
Expression of Genes of Interest in Primary Tissue and Cell Lines Used in This Study
| Brain Region (TPM)* | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Genes | Testis (TPM)* | All (Avg.) | Basal Ganglia† | Cerebellum† | HEK293‡ | MCF7 (RPKM)§ | CAPAN-2 (RPKM)§ | A375 (RPKM)§ | PC3 (RPKM)§ | K562 (RPKM)§ |
| MAGE-A3 | 12.8 | ND | ND | ND | No/low | 0.03 | 0.1 | 175 | 0.8 | 74 |
| MAGE-A12 | 5.9 | 0.2 | 0.3 | 0.1 | No/low | 0.04 | 0.1 | 245 | 0.05 | 87 |
| MAGE-A10 | 3.8 | 0 | ND | ND | No/low | 0 | 0.07 | 74 | 0.04 | 0.3 |
| EPS8L2 | 13.0 | 12.6 | 5.4 | 64.0 | No/low | 109 | 453 | 27 | 151 | 12 |
Highest expression region for MAGE family members; GTEx.9
Highest expression region in the brain for the target gene (average of putamen and nucleus accumbens).
BioGPS,11 below median of >60 cell lines on the U133A Affymetrix chip.
TRON.12
ND indicates no TPM reported; TPM, transcripts per million.