Table 1. Solved structures of the inner membrane protein component of the RND-type of bacterial efflux system.
| Organism | Inner membrane protein |
Year | Protein Data Bank ID | Method |
|---|---|---|---|---|
| Escherichia coli | AcrB | 2002 2006 |
1IWG27 2DHH39 |
X-ray X-ray |
| Pseudomonas aeruginosa | MexB | 2009 | 2V5040 | X-ray |
| E. coli | CusA | 2010 | 3K0741, 3KSS41, 3KSO41 | X-ray |
| Cupriavidus metallidurans | ZneA | 2013 | 4K0E42, 4K0J42 | X-ray |
| Neisseria gonorrhoeae | MtrD | 2014 2020 |
4MT143 6VKS44, 6VKT44 |
X-ray Cryo-EM |
| Campylobacter jejuni | CmeB | 2017 | 5LQ345, 5T0O45 | X-ray |
| Burkholderia multivorans | HpnN | 2017 | 5KHN46, 5KHS46 | X-ray |
| Acinetobacter baumannii | AdeB | 2019 | 6OWS47 | Cryo-EM |
| Mycobacterium smegmatis | MmpL3 | 2019 2019 |
6OR248 6AJF49 |
X-ray X-ray |
Cryo-EM, cryo-electron microscopy; RND, resistance–nodulation–cell division.