Table 2.
The results of longitudinal joint modeling of eGFR and the frequency of acute kidney transplant rejection.
| Variable | Estimate | Standard error | p value | 95% CI | OR | |
|---|---|---|---|---|---|---|
| Ordinal process (estimated glomerular filtration rate) | ||||||
| Age | 0.047 | 0.010 | <0.001 | 0.028 | 0.066 | 1.05 |
| Sex (female) | 0.884 | 0.278 | 0.002 | 0.335 | 1.434 | 2.42 |
| Diabetes (no) | -0.195 | 0.288 | 0.499 | -0.765 | 0.375 | 0.82 |
| ATN (no) | 0.346 | 0.696 | 0.620 | -1.031 | 1.723 | 1.41 |
| DGF (no) | 2.140 | 1.231 | 0.084 | -0.295 | 4.575 | 8.50 |
| CAN (no) | -0.814 | 0.248 | 0.001 | -1.305 | -0.324 | 0.44 |
| Time | -0.005 | 0.030 | 0.879 | -0.064 | 0.055 | 0.99 |
| Random effect standard deviation | 0.322 | 0.041 | ||||
| Count process (acute kidney transplant rejection) | ||||||
| Sex (female) | -0.447 | 0.380 | 0.242 | -1.200 | 0.306 | 0.640 |
| ATG (no) | 0.967 | 0.540 | 0.076 | -0.102 | 2.035 | 2.630 |
| Hypercalcemia (no) | 0.964 | 0.536 | 0.075 | -0.097 | 2.025 | 2.622 |
| Proteinuria (no) | -0.641 | 0.393 | 0.105 | -1.418 | 0.136 | 0.527 |
| Hypertension (no) | -0.450 | 0.426 | 0.293 | -1.294 | 0.393 | 0.638 |
| Time | -0.046 | 0.054 | 0.389 | -0.152 | 0.060 | 0.955 |
| Random effect standard deviation | 0.004 | 0.280 | ||||
| Negative binomial parameter | 0.172 | 0.045 | <0.001 | 0.083 | 0.261 | |
| Correlation between the random intercepts | 0.765 | 0.101 | <0.001 | 0.563 | 0.967 | |
ATG: antithymocyte globulin; DGF: delayed graft function; ATN: acute tubular necrosis; CAN: chronic allograft necrosis; OR: odds ratio; CI: confidence interval.