Table 2.
Ventilation parameters during ECMO support in the survivor and non-survivor groups
| Variable | Before ECMO initiation | After ECMO initiation (immediate) | After 24 hr | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Survivors (n=33) | Non-survivors (n=41) | p-value | Survivors (n=33) | Non-survivors (n=41) | p-value | Survivors (n=33) | Non-survivors (n=41) | p-value | |||
| Vital signs | |||||||||||
| MAP (mm Hg) | 81.67±20.907 | 74.66±17.187 | 0.118 | 77.21±17.453 | 108.36±21.627 | 0.516 | 69.42±24.021 | 64.10±27.300 | 0.382 | ||
| Heart rate (/min) | 108.45±27.602 | 115.20±25.417 | 0.279 | 108.36±21.627 | 111.58±22.191 | 0.532 | 93.21±21.177 | 102.32±19.757 | 0.060 | ||
| Respiratory rate (/min) | 22.94±6.519 | 22.34±5.448 | 0.669 | 19.03±5.457 | 20.02±5.875 | 0.458 | 15.55±4.024 | 16.93±4.891 | 0.196 | ||
| Arterial blood gases | |||||||||||
| pH | 7.26±0.126 | 7.24±0.173 | 0.532 | 7.40±0.088 | 7.38±0.129 | 0.375 | 7.42±0.063 | 7.39±0.108 | 0.198 | ||
| PaO2 (mm Hg) | 63.34±13.155 | 89.34±101.551 | 0.149 | 112.13±89.362 | 109.69±73.128 | 0.897 | 102.22±61.686 | 91.03±93.610 | 0.348 | ||
| PaCO2 (mm Hg) | 58.38±39.804 | 62.09±40.038 | 0.692 | 33.91±12.966 | 35.13±9.500 | 0.644 | 39.04±12.129 | 38.40±8.137 | 0.786 | ||
| HCO3 (mEq/L) | 24.53±8.491 | 26.51±14.242 | 0.484 | 21.09±5.809 | 20.81±7.636 | 0.865 | 24.30±4.443 | 23.69±5.497 | 0.607 | ||
| SaO2 (%) | 86.43±8.899 | 85.73±13.576 | 0.799 | 95.75±4.435 | 94.78±4.744 | 0.371 | 96.16±6.102 | 93.29±8.471 | 0.068 | ||
| Ventilation parameters | |||||||||||
| FiO2 (%) | 97.12±7.184 | 92.8±15.250 | 0.114 | 45.90±13.372 | 52.439±18.678 | 0.096 | 42.27±8.577 | 44.43±17.033 | 0.508 | ||
| PEEP (cmH2O) | 9.70±2.767 | 9.32±2.832 | 0.564 | 8.39±2.370 | 8.39±2.574 | 0.945 | 8.21±1.691 | 8.37±2.129 | 0.717 | ||
| PIP (cmH2O) | 26.24±4.931 | 26.80±5.460 | 0.647 | 22.03±5.323 | 23.37±4.930 | 0.263 | 21.51±4.055 | 22.35±4.894 | 0.432 | ||
Values are presented as mean±standard deviation.
ECMO, extracorporeal membrane oxygenation; MAP, mean arterial pressure; Pa, partial pressure; SaO2, oxygen saturation; FiO2, fraction of inspired oxygen; PEEP, positive end-expiratory pressure; PIP, peak inspiratory pressure.