Table 5.
Cox multivariable proportional hazard regression of factors associated with 28-day mortality (n=74)
| Variable | HR (95% CI) | p-value |
|---|---|---|
| CFB on day 3 | 3.366 (1.528–7.417) | 0.003 |
| Age | 1.005 (0.981–1.030) | 0.669 |
| APACHE II score | 1.000 (0.933–1.072) | 0.997 |
| SOFA score | 1.062 (0.918–1.228) | 0.417 |
| RESP score | 0.916 (0.798–1.052) | 0.214 |
| ECMO type: venovenous ECMO | 0.748 (0.292–1.914) | 0.545 |
| Cause of ARDS: sepsis | 1.859 (0.575–6.012) | 0.301 |
| Duration of MV support prior to ECMO initiation | 0.913 (0.834–1.001) | 0.052 |
| Use of CRRT | 0.482 (0.210–1.107) | 0.085 |
| Complication: acute kidney injury | 1.394 (0.544–3.568) | 0.489 |
| Complication: bleeding | 3.157 (1.434–6.953) | 0.004 |
HR, hazard ratio; CI, confidence interval; CFB, cumulative fluid balance; APACHE II, Acute Physiology And Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; RESP, Respiratory Extracorporeal Membrane Oxygenation Survival Prediction; ECMO, extracorporeal membrane oxygenation; ARDS, acute respiratory distress syndrome; MV, mechanical ventilation; CRRT, continuous renal replacement therapy.