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. 2021 Jan 12;54(2):60–67. doi: 10.1055/a-1324-3517

Table 3 Consensus on concomitant or PRN medication with an antipsychotic depending on clinical situations.

Reduction of excitement PRN for excitement/agitation Depression/anxiety Obsessive compulsive symptoms
Risperidone 2nd 1st 3rd 3rd
Quetiapine 2nd 2nd 2nd 3rd
Olanzapine 2nd 2nd No consensus 3rd
Levomepromazine 2nd 2nd n.a. n.a.
Lorazepam 2nd 2nd n.a. n.a.
Diazepam 3rd 2nd n.a. n.a.
Zotepine 2nd No consensus n.a. n.a.
ECT 2nd n.a. n.a. n.a.
Sodium valproate 2nd 3rd n.a. n.a.
Paliperidone 2nd 3rd n.a. n.a.
Haloperidol 2nd 3rd n.a. n.a.
Aripiprazole 3rd 3rd No consensus 2nd
SSRI n.a. n.a. No consensus 2nd
SNRI n.a. n.a. 2nd 3rd
Lithium n.a. n.a. 2nd 3rd
Chlorpromazine No consensus No consensus n.a. n.a.
Asenapine No consensus No consensus 3rd 3rd
Brexpiprazole 3rd 3rd No consensus 3rd
Sulpiride 3rd 3rd 3rd 3rd
Blonanserin 3rd 3rd n.a. n.a.
Perospirone 3rd 3rd n.a. n.a.
Sultopride 3rd 3rd n.a. n.a.
Fluphenazine 3rd 3rd n.a. n.a.
Perphenazine 3rd 3rd n.a. n.a.
Benzodiazepine n.a. n.a. No consensus 3rd
Mirtazapine n.a. n.a. No consensus 3rd
TCA n.a. n.a. 3rd 3rd
TeCA n.a. n.a. 3rd 3rd
Trazodone n.a. n.a. 3rd 3rd

Abbreviations: ECT=electroconvulsive therapy, n.a.=not available, SNRI=serotonin and norepinephrine reuptake inhibitors, SSRI=selective serotonin reuptake inhibitor, TCA=tricyclic antidepressant, TeCA=tetracyclic antidepressant.