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. 2020 Sep 23;14(2):431–442. doi: 10.1038/s41385-020-00344-9

Fig. 7. Increased moDCs in the lungs of COPD patients.

Fig. 7

Single-cell suspensions were prepared from the lungs of 12 COPD patients and 6 controls without chronic respiratory disease and analyzed by mass cytometry. a Expression of CD11b, CD11c, and HLA-DR in viSNE clusters generated from live, single, CD45+ cells from all patients (total of 400,000 cells). b Abundance (percentage among CD11b+CD11c+HLA-DR+ cells) of the 2 myeloid cell clusters enriched in COPD lungs relative to controls. c Histograms of myeloid cell markers in the 2 cell clusters (identified as moDCs) enriched in COPD lungs. *p < 0.01 compared to control lungs (Mann–Whitney test). Box-and-whisker plots represent median, interquartile range, and range.