Table 1.
Baseline features of pAI and sAI
| Characteristics | pAI (n = 104) | sAI (n = 99) | p |
|---|---|---|---|
|
Gender N (%) Male Female |
39 (37.5%) 65 (62.5%) |
46 (46.5%) 53 (53.5%) |
NS |
|
Age at diagnosis (year) Mean ± SD |
46.5 ± 15.4 | 50.0 ± 17.2 | |
|
Weight (kg) Mean ± SD |
69.4 ± 16.5 | 74.1 ± 18.1 | NS |
|
BMI (kg/m2) Mean ± SD |
25.3 ± 5.4 | 26.9 ± 5.7 | 0.04 |
|
Waist (cm) Mean ± SD |
93.9 ± 17.1 | 96.8 ± 13.2 | NS |
|
Systolic blood pressure (mmHg) Mean ± SD |
119 ± 17 | 123 ± 17 | NS |
|
Diastolic blood pressure (mmHg) Mean ± SD |
75 ± 10 | 79 ± 11 | 0.007 |
| Hypertension N (%) | 21 (20.2%) | 31 (31.3%) | NS |
| Diabetes mellitus N (%) | 16 (15.4%) | 11 (11.1%) | NS |
| Dyslipidemia N (%) | 75 (72.1%) | 69 (69.6%) | NS |
| Cardiovascular events N (%) | 9 (8.6%) | 7 (7.1%) | NS |
| Adrenal crisis N (%) | 15 (14.4%) | 3 (3.0%) | 0.009 |
|
HC-TDD (mg/day) Mean ± SD |
25.8 ± 7.4 | 21.1 ± 8.5 | < 0.001 |
|
HC-KDD (mg/kg/day) Mean ± SD |
0.44 ± 0.17 | 0.33 ± 0.14 | < 0.001 |
Bold values indicate statistically significant values
SD standard deviation, BMI body mass index, HC-TDD hydrocortisone total daily dose, HC-KDD hydrocortisone per-kg-daily dose