Fig. 3.

Cocaine-specific effects on Hsps in BV2 cells and exosomes. BV2 microglial cells were treated with cocaine (10 nM, 100 nM, 1 µM, 10 µM, and 100 µM) for 24 h, and the expression levels of was evaluated in in exosomes. a Hsp70 and b Hsp90 densities derived from dot blot. Statistical significance derived from 5 independent experiment in triplicates is indicated the mean of SD as follows: *p < 0.05; **p < 0.001; and ***p < 0.0001