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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Hypertension. 2021 Mar 1;77(4):1412–1427. doi: 10.1161/HYPERTENSIONAHA.120.16831

Figure 6. Effect of TET1 on STOCs in uterine arteries.

Figure 6.

A and B, Uterine arteries of normoxic control pregnant sheep were treated with scramble control (Ctr siRNA) or TET1 siRNAs for 48 hours and STOC frequency and amplitude were measured after the treatment. Data are means ± SEM of 5 animals in each group; repeated measures ANOVA with the post hoc Bonferroni/Dunn test; *P < 0.05, TET1 siRNA versus Ctr siRNA. C and D, Uterine arteries from high-altitude pregnant sheep were treated with 100 nmol/L miR-210-LNA or negative control (Neg Ctr) in the presence of 3 mmol/L monoethyl fumarate (MEF) under 10.5% O2 for 48 hours. STOC frequency and amplitude were measured after the treatment. Data are means ± SEM of 5 animals in each group; repeated measures ANOVA with the post hoc Bonferroni/Dunn test.