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Death of mice after LMM or DMM injection. Based on survival and weight loss, the MTD of LMM and DMM was determined as approximately 10 and 20 mg/kg, respectively. (n = 4 mice/group)
| Death of mice | ||
|---|---|---|
| Dose | LMM | DMM |
| 10 mg/kg | 0/4 | 0/4 |
| 20 mg/kg | 1/4 | 0/4 |
| 30 mg/kg | 4/4 | 2/4 |
| 40 mg/kg | 4/4 | 4/4 |
