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. Author manuscript; available in PMC: 2022 Mar 15.
Published in final edited form as: J Immunol. 2021 Jan 29;206(6):1297–1314. doi: 10.4049/jimmunol.2000965

FIGURE 2.

FIGURE 2.

TLR3-deficiency attenuates chronic lung disease after viral infection. (a) PAS and hematoxylin staining of lung sections from WT and Tlr3–/– mice at 49 d after SeV infection or SeV-UV. Small scale bar, 500 μm; large scale bar, 250 μm. (b) Lung sections from (a) with hematoxylin and PAS staining colorized red with image analysis. (c) Muc5ac immunostaining of lungs for conditions in (a). Small scale bar, 500 μm; large scale bar, 250 μm. (d) Quantification of red-colorized staining from (b) and immunostaining from (c). (e) Levels of Il13, Muc5ac, and Arg1 mRNA in lungs from WT and Tlr3–/– mice at 49 d after SeV infection or SeV-UV. (f) F4/80 immunostaining of lung sections for conditions in (a). Scale bar, 200 μm. (g) Quantification of immunostaining from (f). All data are representative of three separate experiments (mean and SEM) with at least 5 mice per condition in each experiment. *P<0.01.