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. Author manuscript; available in PMC: 2022 Mar 15.
Published in final edited form as: J Immunol. 2021 Jan 29;206(6):1297–1314. doi: 10.4049/jimmunol.2000965

FIGURE 3.

FIGURE 3.

TRIF-deficiency does not affect acute inflammatory illness after viral infection. (a) Body weights for WT and Trif–/– mice after SeV infection or SeV-UV. (b) Levels of SeV NP RNA in lungs from the same strains of mice after infection with SeV. (c) PAS and hematoxylin staining of lung sections from WT and Trif–/– mice at 5 d after SeV or SeV-UV. Small scale bar, 500 μm; large scale bar, 250 μm. (d) Lung sections from (c) with hematoxylin staining colorized red using image analysis. (e) Quantification of red-colorized staining from (d). (f) Flow cytometry-based levels of total and immune cell populations in lung tissue from WT and Trif–/– mice at indicated time points after SeV infection. (g) Levels of Ccl2 and Ccl7 in lung tissue from WT, Tlr3–/–, and Trif–/– mice at 5 d after SeV infection or SeV-UV. All data are representative of three separate experiments (mean and SEM) with at least 5 mice per condition in each experiment. *P<0.01.