Table 3.
Summary of anti-viral lectins and their EC50 values against SARS-CoV in Vero and Crandell feline kidney cells.
| S. no | Lectins | EC50 (μg/ml) | CC50 (μg/ml) |
|---|---|---|---|
| 1 | GlcNAc-specific agglutinins | ||
| • PallGlcNac | ˃100 | ˃100 | |
| • Nictaba | 1.7 ± 0.3 | ˃100 | |
| 2 | Man/GalNAc-specific agglutinins | ||
| • TL C II | 38 ± 0 | >50 | |
| 3 | Mannose-specific agglutinins | ||
| • APA | 0.45 ± 0.08 | >100 | |
| • CA | 4.9 ± 0.8 | >100 | |
| • EHA | 1.8 ± 0.3 | >100 | |
| 4 | Gal-specific agglutinins | ||
| • Morniga G II | 50 ± 13 | >100 | |
| 5 | Man/Glc-specific agglutinins | ||
| • Cladistris | 7.4 ± 0.2 | >100 |
GlcNac: N-acetyl glucosamine, Man: mannose, Gal: galactose, GalNAc: N-acetyl galactosamine.
Adapted from the study of Keyaerts et al. [53] with permission from Elsevier.