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. 2021 Feb 25;12:636061. doi: 10.3389/fimmu.2021.636061

Figure 5.

Figure 5

Total and differential cell counts (eosinophils, neutrophils, macrophages, and lymphocytes) in bronchoalveolar lavage fluid (A) and concentration of inflammatory cytokines (TNFα, IL-4, IL-5, IL-6, IL-9, IL-13, and IL-33) in lung homogenates of the 3 treatment groups (n=12 per group) (B). Saline: mice sensitized with saline + CFA only (group 1). vehicle/HDM: mice sensitized with HDM at day 0, prophylactic treatment with vehicle at days 12 to 14, and challenge with HDM at day 14 (group 2). hBD-2/HDM: mice sensitized with HDM at day 0, prophylactic treatment with hBD-2 at days 12 to 14, and challenge with HDM at day 14 (group 3). *p < 0.05 when compared to other groups (ANOVA with post-hoc t-test,). hBD-2, human beta-defensin 2; HDM, house dust mite.