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. 2021 Mar 10;4:321. doi: 10.1038/s42003-021-01819-6

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Structure of PKA-C highlighting all communities and their roles in various functions and regulatory mechanisms. CHESCA community matrices for b PKA-C^WT and c PKA-C^DNAJB1 upon binding PKI_5–24. d–e CHESCA community matrices plotted on their corresponding structures. The size of each node is independent of the number of residues it encompasses, meanwhile the weight of each line indicates the strength of coupling between the individual communities.