Skip to main content
. 2021 Mar 10;4:321. doi: 10.1038/s42003-021-01819-6

Fig. 5. Global coordinated response of PKA-CWT and PKA-CDNAJB1 to ligand binding.

Fig. 5

Coordinated chemical shift changes analyzed with CONCISE for a PKA-CWT and b PKA-CDNAJB1. Changes in the free energy of binding of c PKA-CWT and d PKA-CDNAJB1 to ATPγN and PKI5–24. Black lines indicate the values obtained from ITC and pink lines correspond to values obtained from NMR measurements.