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. 2021 Mar 11;12(3):256. doi: 10.1038/s41419-021-03548-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — siRNA was used to interfere the expression of endogenous FGFR2 (a). siRNA interference did not change the response of RBE cells to BGJ398 (b) or AZD4547 (c). Dose-response curves for BGJ398 (d) and AZD4547 (e) in RBE cells. The viability of RBE cells expressing different FGFR2 fusions was detected by CCK8 assay after treatment with indicated concentration of BGJ398 or AZD4547.