Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 10;11:5558. doi: 10.1038/s41598-021-84840-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Establishment of SARS-CoV-2-S-mediated cell–cell fusion system. (a) Western blot analysis of S protein expression in 293 T cells transfected with pCDNA3.1-SARS-S and pCDNA3.1-SARS2-S. The two blot images derived from different gels which were run using the same samples. (b) Western blot analysis of ACE2/293 T cells that express ACE2 protein. The two blot images derived from different gels which were run using the same samples. The full blot images for a and b are included in the supplementary figures. (c) Imaging of SARS-CoV-S/293 T and SARS-CoV-2-S/293 T cell fusion with ACE2/293 T cells at 4 h and 24 h. Non-S-transfected cells serve as a negative control. Scale bar equals 400 µm in all figures.