Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 25;12:599296. doi: 10.3389/fimmu.2021.599296

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Farazuddin, Landers, Janczak, Lindsey, Finkelman, Baker and O’Konek

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Intranasal administration of NE without allergen does not suppress the allergic response. (A–C) Mice were sensitized with OVA and peanut-alum and treated i.n. with 3 administrations of PBS (sensitized control), OVA-NE (OVA-NE) or NE only (no antigen) or Mice were challenged orally with OVA and temperature change and symptoms of anaphylaxis were monitored. Serum MCPT-1 levels were determined by ELISA. (D–F) In a separate experiment, mice were similarly sensitized with OVA and peanut with alum and treated i.n. with 3 administrations of PBS (sensitized control) or hepatitis B surface antigen-NE (HBsAg-NE). Statistically significant differences (p < 0.05) are indicated by *.