Table 2.
Incidence of aneuploidy and CNV discovered in NT 3–4 mm and > 4 mm sub-groups.
| Anomalies | NT 3–4 mm (N = 81) | NT > 4 mm (N = 27) | RR† | P | ||
|---|---|---|---|---|---|---|
| N | % | N | % | |||
| Normal | 62 | 76.54 | 15 | 55.56 | 0.73 | 0.037* |
| Aneuploidy | 12 | 14.81 | 9 | 33.33 | 2.25 | 0.035* |
| Pathogenic CNV | 6 | 7.41 | 3 | 11.11 | 1.50 | 0.546 |
| VOUS CNV | 1 | 1.24 | 0 | 0 | 0 | 0.562 |
Abbreviations: NT: nuchal translucency; CNV, copy-number variation; VOUS, variants of unknown significance; RR, relative risk.
†Relative risk is calculated as % cases of the anomaly in the NT > 4 mm group/% cases of the corresponding anomaly in the NT 3–4 mm group, e.g. RR of aneuploidy: 33.33%/14.81% = 2.25. NT 3–4 mm group is used as the reference.
* P < 0.05.