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. 2021 Mar 10;11:5608. doi: 10.1038/s41598-021-84853-y

Table 1.

Demographic characteristics of patients with acute myocardial infarction who later developed adverse cardiovascular events (ACE) and direct medical costs for the first hospitalization, life-time medical costs (LMC) for in- and out-patient stratified by major comorbidities and receiving percutaneous coronary intervention (PCI).

Receiving PCI Without major comorbidities With major comorbidities
Yes No Yes No
Total 26,193 12,248 4369 4573
No. of male (%) 21,675 (82.8%) 9202 (75.1%) 3238 (74.1%) 3109 (68.0%)
Age (mean ± SD) 60.9 ± 13.4 64.9 ± 13.7 70.3 ± 11.9 72.8 ± 12.1
No. of STEMI (%) 4306 (16.4%) 2863 (23.4%) N/A N/A
No. of NSTEMI (%) 21,887 (83.6%) 9385 (76.6%) N/A N/A
No. of deceased (%) 5802 (22.2%) 5397 (44.1%) 2382 (54.5%) 3504 (76.6%)
Direct medical costs for the first hospitalization (US$) 5486 4728 N/A N/A
Follow-up outpatient LMC (US$) 23,975 18,860 N/A N/A
Follow-up inpatient LMC (US$) 36,286 29,823 N/A N/A
ACE (No. events/population)
Within 1 year
 Acute myocardial infarction 1317 (5.0%) 1529 (12.5%) 322 (7.4%) 597 (13.1%)
 Heart Failure 753 (2.9%) 499 (4.1%) 300 (6.9%) 363 (7.9%)
 Stroke 465 (1.8%) 271 (2.2%) 171 (3.9%) 163 (3.6%)
Within 3 years
 Acute myocardial infarction 1739 (6.7%) 1751 (14.3%) 403 (9.2%) 688 (15.0%)
 Heart Failure 1096 (3.5%) 688 (5.6%) 400 (9.2%) 493 (10.8%)
 Stroke 831 (2.6%) 510 (4.2%) 279 (6.4%) 245 (5.4%)
Within 18 years
 Acute myocardial infarction 2749 (10.5%) 2247 (18.3%) 517 (11.8%) 783 (17.1%)
 Heart Failure 1732 (6.6%) 1117 (9.1%) 510 (11.7%) 602 (13.2%)
 Stroke 1652 (6.3%) 983 (8.0%) 404 (9.2%) 323 (7.1%)

Major comorbidities include ischemic stroke, hemorrhagic stroke, chronic kidney diseases, liver cirrhosis, chronic obstructive pulmonary diseases, and documental malignancy.

SD standard deviation, STEMI ST-segment elevation myocardial infarction, NSTEMI non ST-segment elevation myocardial infarction.