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. Author manuscript; available in PMC: 2022 Mar 19.
Published in final edited form as: J Mol Biol. 2020 Sep 11;433(6):166648. doi: 10.1016/j.jmb.2020.09.007

Figure 2. Examples of native-like nucleosomes studied by X-ray crystallography and cryo-EM.

Figure 2.

(A) The crystal structure of 147 bp MMTV-A nucleosome core particle [15]. (B) Cryo-EM reconstruction of 186 bp ABL1 enhance (N1) nucleosome. The FoxA1 binding sites (eG and eH) are shown in magenta and yellow colors [19]. (C) Cryo-EM density map for the 162 bp human LIN28B DNA and DNA motifs for binding of transcription factor Oct4 [20].