Fig. 2.

HbA1c and weight change. a Absolute mean HbA1c was 8.5% (95% CI 8.2–8.7%) at baseline and 7.7% (95% CI 7.4–8.0%) and 7.5% (95% CI 7.2–7.7%) at 3 and 6 months, respectively, in comparison to pre-baseline (8.3%, 95% CI 8.0–8.6%). b Mean weight loss was 1.6 kg (95% CI 2.4–0.91 kg) and 3.0 kg (95% CI 4–2 kg) at 3 and 6 months, respectively after treatment with semaglutide compared to baseline. c BMI was significantly lower at 3 months (mean 35 kg/m² 95% CI 33–36 kg/m²) and 6 months (34 kg/m² 95% CI 33–36 kg/m²) after switching to semaglutide compared to baseline (mean 35 kg/m², 95% CI 34–37 kg/m²). Graphically represented are median values and interquartile range. CI confidence interval, ***p < 0.005, ****p < 0.0001