Table 1.
Animals | Sex | Age (years) | MRI (hemisphere) | Experiment durationa (weeks) | EAE scoreb | First lesion appearancec (weeks) |
---|---|---|---|---|---|---|
M1 | F | 12.1 | PM (left) | 18 | 41 | 11 |
M2 | F | 6.7 | PM (right) | 268 | 28 | 8 |
M3 | F | 3.2 | PM (left) | 5 | 18 | 2 |
M4 | F | 4.3 | PM (left) | 12 | 11 | 3 |
M5 | F | 4.5 | PM (right) | 4 | 10 | 3 |
M6 | F | 1.5 | PM (left) | 31 | 8 | No WM lesion |
M7 | F | 9.6 | PM (right) | 15 | 17 | No WM lesion |
M8 | F | 4.8 | PM (left) | 10 | 18 | 7 |
M9 | M | 3 | PM (right) | 16 | 41 | 11 |
M10 | M | 7.3 | In vivo/PM (right) | 7 | 24 | 5 |
M11 | F | 7.7 | In vivo | 7 | 28 | 5 |
M12 | F | 5.9 | PM (left) | NA | 0 | NA |
M13 | F | 4.9 | PM (left) | NA | 0 | NA |
M14 | F | 3.1 | In vivo | NA | 0 | NA |
Note: F, female; M, male; PM, postmortem.
aExperiment duration from EAE induction to sacrifice.
bEAE score at the terminal day. See Villoslada et al. 2000.
cTime between EAE immunization and first WM lesions on MRI.