Table 1.

Innate lymphoid cell subsets and their contributions in inflammatory disorders.

	ILC1	ILC2	ILC3
Transcription factor	T-bet	GATA-3	RORγt
Activated cytokines	IL-12, IL-15, IL,18	IL-25, IL-33	IL-1β, IL-23
Mediators produced	IFN-γ, TNF-α	IL-4, IL-5, IL-13	IL-17, IL-22, GM-CSF
Function	Inflammation	Immunity to helminths	Lymphoid tissue development, Intestinal homeostasis, Immunity to extracellular bacteria
Disease Associations	Inflammatory conditions, Inflammatory bowel disease	Allergy and asthma	Inflammatory bowel disease