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. 2021 Feb 25;11:586771. doi: 10.3389/fonc.2021.586771

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Copyright © 2021 Huang, Tian, Zhang, Liu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Rab12 affected radiosensitivity of cervical cancer cells. (A) Western blot analysis of Rab12 expression after transfection of shRab12 lentivirus. (B, C) The effects of radiation on cell proliferation and viability of SiHa-ShRab12 and control cells were detected by the colony formation and CCK-8 assays. (D) Western blot analysis of Rab12 expression after transfection of pENTER-Rab12, adenovirus vector overexpressing Rab12. (E, F) The effects of radiation on cell proliferation and viability of C33A cells overexpression Rab12 were detected by the colony formation and CCK-8 assays. Data presented as mean ± SD from three independent experiments, *p < 0.05, **p < 0.01, ***p < 0.001.