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. 2021 Feb 25;8:633706. doi: 10.3389/fvets.2021.633706

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Copyright © 2021 Xiao, Zhang, Yan, Geng, Wang, Xu, Wang, Zhang, Huang, Pang, Yang and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of FMDV VLPs. (A) Protein purification by gel filtration chromatography. (B) SDS-PAGE analysis of peak a, and peak b proteins obtained from gel filtration chromatography. Lane 1: peak a; lane 2: peak b. (C) DLS analysis of the size distribution of proteins in peaks a and b. (D) Protein visualization of peak a by TEM, the red arrow indicating the VLPs. (E) Protein visualization of peak B by TEM; the black arrow indicated the unassembled proteins. Magnification of 42,000×, the scale bar indicates 50 nm.