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Quantitative analysis of two analogous FMDV proteins by the solution competitive ELISA concerning their binding profiles with different monoclonal antibodies.
| Neutralizing mAbs | IC50 (ng/mL) | Relative binding activity (VLPs over unassembled) | |
|---|---|---|---|
| Unassembled | VLPs | ||
| F21-64 (Site1a, 5) | 121,754 | 19,245 | 6.3 |
| F21-48 (Site1a, 5) | 430,916 | 123,724 | 3.5 |
| F21-41 (Site2) | 146,927 | 12,449 | 12 |
| F21-58 (Site3) | 45,888 | 4,598 | 10 |
