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. 2021 Feb 25;8:651999. doi: 10.3389/fvets.2021.651999

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Copyright © 2021 Puente, Argüello, Mencía-Ares, Gómez-García, Rubio and Carvajal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phylogenetic tree based on the complete S-gene sequences including all Spanish enteric porcine coronaviruses available in GenBank. Numbers along the tree represents the confidence value for a given internal branch based on 500 Bootstrap replicates (only values >70 are shown). The symbols above the strains stand out the Spanish PEDV isolates of this study. The filled circles identified the isolates sequenced in this research and the filled triangles identified the isolates previously sequenced by de Nova et al. (15). GenBank accession number, province and year of the outbreak are also shown below the strains. The genogroups and subgroups referred in the text are included on the right of the tree. Scale bars indicate nucleotide substitutions per site. Black, pre-2000 isolates; Red, 2014 isolates; Gray, 2015 isolates; Purple, 2016 isolates; Yellow, 2017 isolates; Green, 2018 isolates; Blue, 2019 isolates.