Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 25;9:625540. doi: 10.3389/fcell.2021.625540

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Li, Miao, Chen and Xiong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of SIRT6 inhibition on the transcriptome profile of porcine oocytes. (A) Heatmap illustration displayed the differentially expressed genes (DEGs) between control and SIRT6-inhibited oocytes. (B) Volcano plot showed the DEGs in SIRT6-inhibited oocytes compared to controls. Downregulated, blue; upregulated, red. (C) RNA sequencing (RNA-seq) results of selected genes in SIRT6-inhibited oocytes compared to controls. (D) Validation of RNA-seq data by quantitative RT-PCR in control (blue) and SIRT6-inhibited (red) oocytes. Data were presented as the mean percentage (mean ± SEM) of at least three independent experiments. **P < 0.01, *P < 0.05. (E) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of DEGs in SIRT6-inhibited oocytes in comparison with controls.