FIGURE 2.
Sequence variation in the 5′ regions of the 129 and B6 Olfr17 alleles. (A) Schematic representation of the Olfr17 gene structure. The olfactory receptor gene Olfr17 contains two exons, and the second exon contains the complete coding sequence (CDS) of the gene. The genomic coordinates are according to the GRCm38/mm10 assembly and display the positions of the transcription start site (TSS) and of the last nucleotide within the 5′-UTR. The presumed promoter region is indicated. (B) Schematic representation of the 5′ region of the Olfr17 gene of the B6 and 129 mouse strain alleles showing the positions of the CpG dinucleotides. There are two single nucleotide polymorphisms (SNPs) in this region which lead to the generation of two additional CpGs in the 129 Olfr17 allele (at positions –128 and +33).
