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. 2021 Feb;10(2):965–980. doi: 10.21037/tlcr-21-146

Table 1. Patient characteristics.

Characteristic PD-L1 (n=145) B3GNT3 (n=145)
Positive (>1%) Negative (<1%) P value Positive Negative P value
Age, years, median [range] 61 [40–75] 60 [28–84] 0.345a 60 [28–84] 62 [45–75] 0.279a
Male:female 22:17 17:60 0.164b 56:67 12:10 0.435b
Smoking 0.592b 0.064b
   Yes 10 (25.6%) 32 (30.2%) 32 (26.0%) 10 (45.5%)
   No 29 (74.4%) 74 (69.8%) 91 (74.0%) 12 (54.5%)
Location 0.869b 0.398b
   Left upper lobe 12 (30.8%) 40 (37.7%) 41 (33.3%) 11 (50.0%)
   Left lower lobe 6 (15.4%) 11 (10.4%) 14 (11.4%) 3 (13.6%)
   Right upper lobe 9 (23.1%) 25 (23.6%) 30 (24.4%) 4 (18.2%)
   Right middle lobe 4 (10.3%) 8 (7.5%) 12 (9.8%) 0 (0.0%)
   Right lower lobe 8 (20.5%) 22 (20.8%) 26 (21.1%) 4 (18.2%)
Clinical T stage (AJCC 8th ed.) 0.086c 0.104c
   pT1a 1 (2.6%) 3 (2.8%) 2 (1.6%) 2 (9.1%)
   pT1b 11 (28.2%) 14 (13.2%) 23 (18.7%) 2 (9.1%)
   pT1c 7 (17.9%) 16 (15.1%) 22 (17.9%) 1 (4.5%)
   pT2a 12 (30.8%) 59 (55.7%) 59 (48.0%) 12 (54.5%)
   pT2b 4 (10.3%) 7 (6.6%) 9 (7.3%) 2 (9.1%)
   pT3 4 (10.3%) 5 (4.7%) 7 (5.7%) 2 (9.1%)
   pT4 0 (0.0%) 2 (1.9%) 1 (0.8%) 1 (4.5%)
Clinical N stage (AJCC 8th ed.) 0.990b 0.946b
   pN0 29 (74.4%) 80 (75.5%) 93 (75.6%) 16 (72.7%)
   pN1 3 (7.7%) 8 (7.5%) 9 (7.3%) 2 (9.1%)
   pN2 7 (17.9%) 18 (17.0%) 21 (17.1%) 4 (18.2%)
TNM stage (AJCC 8th ed.) 0.389c 0.123c
   IA1 1 (2.6%) 3 (2.8%) 2 (1.6%) 2 (9.1%)
   IA2 11 (28.2%) 14 (13.2%) 23 (18.7%) 2 (9.1%)
   IA3 6 (15.4%) 15 (14.2%) 20 (16.3%) 1 (4.5%)
   IB 8 (20.5%) 42 (39.6%) 42 (34.1%) 8 (36.4%)
   IIA 1 (2.6%) 3 (2.8%) 2 (1.6%) 2 (9.1%)
   IIB 4 (10.3%) 8 (7.5%) 11 (8.9%) 1 (4.5%)
   IIIA 7 (17.9%) 17 (16.0%) 19 (15.4%) 5 (22.7%)
   IIIB 1 (2.6%) 3 (2.8%) 3 (2.4%) 1 (4.5%)
   IVA 0 (0.0%) 1 (0.9%) 1 (0.8%) 0 (0.0%)
EGFR mutation 0.615b 0.039b
   Yes 24 (61.5%) 70 (66.0%) 84 (68.3%) 10 (45.5%)
   No 15 (38.5%) 36 (34.0%) 39 (31.7%) 12 (54.5%)

a, Wilcoxon test; b, Pearson’s chi-Square T test; c, Fisher’s exact test.