Table 3. Univariate and multivariate analysis of clinicopathological variables for DFS in lung adenocarcinoma.
Subgroup | Univariable analysis | Multivariable analysis | |||
---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | ||
Age | |||||
>60 years | 1.00 | 1.00 | |||
≤60 years | 0.69 (0.30 to 1.61) | 0.401 | 0.40 (0.15 to 1.08) | 0.069 | |
Sex | |||||
Male | 1.00 | 1.00 | |||
Female | 1.69 (0.72 to 3.95) | 0.228 | 2.43 (0.77 to 7.65) | 0.129 | |
Smoking | |||||
No | 1.00 | 1.00 | |||
Yes | 1.13 (0.44 to 2.89) | 0.803 | 4.43 (1.29 to 15.13) | 0.018 | |
Pathological T stage | |||||
T1a | 1.00 | 1.00 | |||
T1b | 0.00 (0.00 to 0.00) | 0.975 | 0.00 (0.00 to 0.00) | 0.976 | |
T1c | 0.18 (0.02 to 1.72) | 0.135 | 0.18 (0.01 to 2.32) | 0.190 | |
T2a | 0.14 (0.01 to 1.54) | 0.107 | 0.17 (0.01 to 2.53) | 0.200 | |
T2b | 0.15 (0.02 to 1.24) | 0.078 | 0.18 (0.02 to 1.78) | 0.144 | |
T3 | 0.81 (0.09 to 7.30) | 0.853 | 2.13 (0.16 to 27.99) | 0.565 | |
T4 | 2.37 (0.28 to 20.12) | 0.429 | 6.18 (0.50 to 76.07) | 0.155 | |
Pathological N stage | |||||
N0 | 1.00 | 1.00 | |||
N1 | 0.62 (0.22 to 1.72) | 0.358 | 2.31 (0.65 to 8.24) | 0.195 | |
N2 | 0.97 (0.19 to 4.99) | 0.968 | 0.70 (0.11 to 4.55) | 0.711 | |
B3GNT3 expression | |||||
Negative | 1.00 | 1.00 | |||
Positive | 1.97 (0.77 to 5.04) | 0.158 | 3.30 (1.04 to 10.50) | 0.043 |